NMR with Proteins and Nucleic Acids

NMR with Proteins and Nucleic Acids

Initial observations of the physical phenomenon of nuclear magnetic reso­ nance (NMR) date back to the late 1940's, but the use of this technique for investigations of complex biological systems has become attractive only during the last decade. Such applica­ tions include studies of biomacromolecular structure and function, work on biological membranes, in vivo studies of biochemical processes...

NMR of proteins and nucleic acids

This report highlights key papers, published this year, that describe advances in the development and application of NMR techniques to the study of proteins and nucleic acids. Many of the sections presented below reflect evolving trends in recent methodology developments, such as in automated NMR, membrane protein NMR and paramagnetic relaxation enhancement methods. Automated NMR methods are no...

Nucleic acids and proteins

Nucleic Acids and Proteins

NMR methods for studying quadruplex nucleic acids.

Solution NMR spectroscopy has traditionally played a central role in examining quadruplex structure, dynamics, and interactions. Here, an overview is given of the methods currently applied to structural, dynamics, thermodynamics, and kinetics studies of nucleic acid quadruplexes and associated cations.